Assessment of the Deep Tech Ecosystem for Early-stage Entrepreneurship and Investment in Chile

Peer Reviewed icon Peer Reviewed
Author
Díaz, Sandra ;
Andrade, Jorge ;
Venegas, Bernardita ;
Monsalve, Rodrigo ;
Barindelli, Elena ;
Pribnow, Stefan ;
Date issued
January 2026
Subject
Science and Technology;
Startup;
Innovation;
Innovation Ecosystem;
Biotechnology;
Research and Development;
Entrepreneurship;
Investment;
Finance;
Artificial Intelligence;
Venture Capital
JEL code
G24 - Investment Banking • Venture Capital • Brokerage • Ratings and Ratings Agencies;
M13 - New Firms • Startups;
O33 - Technological Change: Choices and Consequences • Diffusion Processes
Country
Chile
Category
Technical Notes
This study is developed in a context of accelerated global technological change, in which frontier technologies or Deep Tech based on advanced science and long R&D cycles, are acquiring a strategic role for competitiveness, technological sovereignty, and the response to social, environmental, and productive challenges. While countries such as the United States, Germany, France, and Spain have advanced with specific national strategies, in Latin America and particularly in Chile the Deep Tech ecosystem remains at an early stage, though with clear signs of maturation and high potential.

The objective of the report is to provide a comprehensive and up-to-date diagnosis of Chiles early-stage Deep Tech entrepreneurship and investment ecosystem, identifying its capabilities, key actors, structural gaps, and strategic opportunities from a systemic perspective. The analysis highlights important advances in scientific, institutional, and support capacities, driven by the creation of the Ministry of Science, pioneering public programs, and a growing network of hubs, technology centers, and early-stage funds particularly in biotechnology, artificial intelligence, advanced materials, and clean technologies.

Nevertheless, critical challenges persist: weak linkages between science and business, limited availability of specialized financing, bottlenecks in scaling infrastructure, and an entrepreneurial culture with relatively low international ambition. Based on these findings, the study proposes five strategic pillars aimed at strengthening governance, financing, capabilities, talent, and internationalization, in order to consolidate Chile as a regional Deep Tech hub in Latin America.
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